Citicoline sodium cusbadu waa dhexdhexaad aan sun ahayn oo ku jirta isku-dhafka noolaha ee fosfotidylcholine ee choline. Daraasaduhu waxay muujinayaan in Citicoline sodium cusbada ay kordhin karto cufnaanta daawada dopamine. Intaa waxaa dheer, Citicoline sodium cusbadu waxay keentaa korodhka heerarka hoormoonka Adrenocorticotropic ee hormoonka sii daaya Corticotropin (CRH) si madaxbannaan. Hormoonnada kale ee dhidibka hypothalamic-pituitary-adrenal ayaa sidoo kale kordhay sida LH, FSH, GH iyo TSH. Daraasado lagu sameeyay unugyada maskaxda ayaa muujinaya in Citicoline sodium cusbada ay dib u celin karto saameynta sunta ah ee ay keento hypoxia, ischemia, iyo dhaawacyada. Waxaa la soo jeediyay in sifooyinkan neuroprotective ee Citicoline sodium cusbada ay ku lug yeelan karaan xoojinta nidaamka glutathione antioxidative intracellular glutathione, hoos u dhigista fosfolipase A, firfircoonida iyo ka hortagga hoos u dhaca fosfolipid, iyo ka hortagga glutamate neurotoxicity.
Erayada muhiimka ah:CDP-choline-Na, CDP-coline, Citicoline sodium
Citicoline Sodium waxaa loo isticmaalaa in lagu daweeyo luminta xusuusta da'da, cudurada maskaxda sida istaroogga, waallida, iyo sidoo kale dhaawacyada madaxa. Cilmi baaris ayaa muujisay in ay kordhiso kiimikada loo yaqaan phosphatidylcholine taas oo muhiim u ah shaqada maskaxda. Citicoline waxay sidoo kale hoos u dhigi kartaa dhaawaca unugyada maskaxda marka maskaxdu dhaawacdo. Citicoline Sodium ayaa sidoo kale la sheegay in ay ka caawiso maareynta miisaanka marka loo isticmaalo kabka cuntada.
Citicoline Sodium waa wakiilka firfircoonida neuron ee ugu badan ee tirada hadda jirta, waxay leedahay codsigan soo socda:
(1) waxay yareeyaan caabbinta xididdada maskaxda, waxay kordhiyaan socodka dhiigga maskaxda, kor u qaadida dheef-shiid kiimikaadka maskaxda, hagaajinta wareegga maskaxda;
(2) xoojinta shaqada dhismaha reticular ee asliga maskaxda, xoojinta shaqada nidaamka pyramidal, hagaajinta curyaannimada dhaqdhaqaaqa, kor u qaadista Yelkin TTS synthesis, hagaajinta dheef-shiid kiimikaadka maskaxda, waxay la wadaagi kartaa polypeptide maskaxda, oo leh is-dhexgalka hagaajinta shaqada maskaxda;
(3) Tilmaamaha ugu muhiimsan waa qalliinka maskaxda ee degdega ah iyo maskaxda Qalliinka ka dib miyir-qabka;
(4) shaqada waxay sidoo kale u keentay habdhiska dhexe ee neerfayaasha dhaawac ba'an kiliinikada iyo qaska miyirka, Parkinsonism, tinnitus iyo luminta maqalka neerfaha, ku sumowga hypnotic iwm;
(5) sanadihii ugu dambeeyay ischemia apoplexy, arteriosclerosis maskaxda, waallida infarct multi-infarct, waallida waayeelka, fayraska encephalitis ee dhallaanka iwm ayaa si weyn loogu isticmaalaa kiliinikada.
Waqtiga boostada: Feb-02-2025