Daraasad dhowaan la sameeyay ayaa daaha ka qaaday in ragga qaata cirbadaha testosterone undecanoate ee muddada dheer ay u badan tahay inay u hoggaansamaan daawadooda marka la barbardhigo kuwa qaata cirbadaha testosterone propionate ee gaaban.Natiijooyinku waxay muujinayaan muhiimadda ay leedahay qaababka habboon ee daaweynta testosterone si loo hubiyo ballanqaadka bukaanka ee daaweynta.
Daraasadda, oo ku lug leh falanqaynta dib-u-eegis ee xogta laga helay ragga 122,000 ee Maraykanka, marka la barbardhigo heerarka u hoggaansanaanta ragga ee lagu daaweeyay testosterone undecanoate iyo kuwa lagu daaweeyay cypionate testosterone.Natiijooyinka waxay muujiyeen in inta lagu jiro 6 bilood ee ugu horreeya ee daaweynta, labada kooxoodba waxay lahaayeen heerar isku mid ah.Si kastaba ha noqotee, sida muddada daawaynta ay ka soo baxday 7 ilaa 12 bilood, kaliya 8.2% bukaannada qaata testosterone cypionate ayaa sii waday daaweynta, marka la barbardhigo 41.9% muhiim ah oo bukaannada qaata testosterone undecanoate.
Dr. Abraham Morgenthaler, oo ah kaaliyaha borofisar qaliinka ee waaxda urology ee xarunta Beth Israel Deaconess Medical Center ee Dugsiga Caafimaadka Harvard, ayaa muujiyay muhiimada natiijooyinkan.Waxa uu yidhi, "Caddaynta waxay soo jeedinaysaa in noocyo badan oo ku habboon daaweynta testosterone, sida irbado muddada dheer, ay muhiim u tahay rabitaanka ragga qaba yaraanta testosterone si ay u sii wadaan daaweynta."Dr. Morgenthaler wuxuu ku nuuxnuuxsaday aqoonsiga sii kordhaya ee yaraanta testosterone oo ah xaalad caafimaad oo muhiim ah wuxuuna iftiimiyay faa'iidooyinka caafimaad ee ballaadhan ee daaweynta testosterone ay bixin karto, oo ay ku jiraan hagaajinta xakamaynta sonkorta dhiigga, hoos u dhigidda baruurta, korodhka murqaha, niyadda wanaajinta, cufnaanta lafaha, iyo xitaa yaraynta. dhiig yarida.Si kastaba ha ahaatee, garashada faa'iidooyinkan waxay ku xiran tahay ilaalinta u hoggaansanaanta daaweynta.
Daraasadda, oo ay sameeyeen Dr. Morgenthaler iyo asxaabtiisa, waxay ka faa'iideysteen xogta Veradigm database, taas oo soo ururisa xogta diiwaanka caafimaadka elektaroonigga ah xarumaha bukaan-socodka ee Maraykanka.Cilmi-baadhayaashu waxay diiradda saareen ragga da'doodu tahay 18 iyo kuwa ka weyn kuwaas oo bilaabay daaweynta testosterone la isku duro ee undecanoate ama testosterone cypionate inta u dhaxaysa 2014 iyo 2018. Xogta, oo la soo ururiyay 6-bilood gudahood ilaa July 2019, ayaa u oggolaaday cilmi-baarayaashu inay qiimeeyaan u hoggaansanaanta daaweynta iyadoo lagu saleynayo waqtiga ballamaha iyo joojinta kasta, isbeddelka rijeetada, ama dhammaystirka daawaynta testosterone ee asal ahaan loo qoray.
Gaar ahaan, u hoggaansanaanta daawaynta ee kooxda testosterone undecanoate waxaa lagu qeexay farqiga u dhexeeya maalmaha 42 ee u dhexeeya dhammaadka taariikhda ballanta koowaad iyo taariikhda bilawga ballanta labaad, ama farqiga u dhexeeya maalmaha 105 ee u dhexeeya ballamaha xiga.Kooxda cypionate ee testosterone, u hoggaansanaan la'aanta ayaa lagu qeexay in ka badan 21 maalmood oo u dhexeeya balamaha.Marka lagu daro heerarka u hoggaansanaanta, baarayaashu waxay falanqeeyeen arrimo kala duwan sida isbeddelka miisaanka jidhka, BMI, cadaadiska dhiigga, heerarka testosterone, heerarka dhacdooyinka cusub ee wadnaha, iyo arrimaha khatarta ah ee khuseeya bilaha 3 ka hor intaan la duri karin bilaha 12 ka dib bilawga. daaweynta.
Natiijooyinkani waxay iftiiminayaan muhiimadda ay leedahay cirbadaha testosterone ee muddada-dheer si kor loogu qaado u hoggaansanaanta daaweynta iyo kordhinta faa'iidooyinka suurtagalka ah ee daaweynta testosterone.Ragga qaba yaraanta testosterone waxay si weyn uga faa'iideysan karaan qaababka ku habboon ee daaweynta, hubinta sii wadida iyo dhiirigelinta ballanqaadka muddada dheer si loo hagaajiyo caafimaadkooda iyo guud ahaan fayo-qabka.
Waqtiga boostada: Jul-07-2023